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J Cutan Pathol ; 50(5): 396-399, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36820822

RESUMO

Perineurioma is a benign peripheral nerve sheath tumor. Several subtypes have been described, including plexiform, reticular, and sclerosing. The reticular variant has been previously described as having a net or lace-like growth pattern consisting of large anastomosing cords of spindle-shaped cells. We report a case of an 11-year-old male who presented with a 2-year history of a slowly enlarging, tan-white lesion on the finger. Microscopically, the lesion consisted of cells with ovoid nuclei and delicate, elongate cytoplasmic processes, arranged in a microreticular pattern. The lesional cells were markedly positive for epithelial membrane antigen and claudin-1. Based on these features and the unusual morphology, the case was called a microreticular perineuroma. The patient underwent complete excision of the lesion with no recurrence 9 months after follow-up. To our knowledge, this is the first reported case of this morphologic variant. Awareness of this entity is important to avoid inappropriate management.


Assuntos
Biomarcadores Tumorais , Neoplasias de Bainha Neural , Masculino , Humanos , Criança , Imuno-Histoquímica , Neoplasias de Bainha Neural/patologia , Dedos/patologia , Proliferação de Células
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